منابع مشابه
Convergent evolution of clustering of Iroquois homeobox genes across metazoans.
Vertebrate and Drosophila Iroquois genes are organized in clusters of 3 genes sharing blocks of conserved regulatory sequences. Here, we report a 3-gene cluster in the basal, preduplicative chordate amphioxus. Surprisingly, however, the origin of the amphioxus cluster is independent of those in vertebrates and drosophilids. Investigation of genomic organization of Iroquois genes in other 17 met...
متن کاملThe Iroquois model: using temporal dynamics to separate speakers
We describe a system that can separate and recognize the simultaneous speech of two speakers from a single channel recording and compare the performance of the system to that of human subjects. The system, which we call Iroquois, uses models of dynamics to achieve performance near that of human listeners. However the system exhibits a pattern of performance across conditions that is different f...
متن کاملA dual requirement for Iroquois genes during Xenopus kidney development.
The Iroquois (Irx) genes encode evolutionary conserved homeoproteins. We report that Xenopus genes Irx1 and Irx3 are expressed and required during different stages of Xenopus pronephros development. They are initially expressed during mid-neurulation in domains extending over most of the prospective pronephric territory. Expression onset takes place after kidney anlage specification, but before...
متن کاملIroquois genes influence proximo-distal morphogenesis during rat lung development.
Lung development is a highly regulated process directed by mesenchymal-epithelial interactions, which coordinate the temporal and spatial expression of multiple regulatory factors required for proper lung formation. The Iroquois homeobox (Irx) genes have been implicated in the patterning and specification of several Drosophila and vertebrate organs, including the heart. Herein, we investigated ...
متن کاملIroquois homeodomain transcription factors in heart development and function.
Numerous cardiac transcription factors play overlapping roles in both the specification and proliferation of the cardiac tissues and chambers during heart development. It has become increasingly apparent that cardiac transcription factors also play critical roles in the regulation of expression of many functional genes in the prenatal and postnatal hearts. Accordingly, mutations of cardiac tran...
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ژورنال
عنوان ژورنال: Science
سال: 1884
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.ns-4.95.486-b